Cultured Human Dermal Fibroblasts do Produce Cortisol

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Cultured human dermal fibroblasts do produce cortisol.

TO THE EDITOR Known steroidogenic functions of the skin that are represented by the synthesis and metabolism of androgens and estrogens (Chen et al., 2002; Zouboulis and Degitz, 2004) probably include corticosteroids (Slominski et al., 2000; Slominski, 2005). Thus, the skin expresses both the genes and proteins involved in the synthesis of adrenal corticosteroids (Slominski et al., 1996, 1999, ...

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ژورنال

عنوان ژورنال: Journal of Investigative Dermatology

سال: 2006

ISSN: 0022-202X

DOI: 10.1038/sj.jid.5700204